{"id":6036,"date":"2021-11-10T11:53:15","date_gmt":"2021-11-10T11:53:15","guid":{"rendered":"https:\/\/upbeat-bassi.138-201-129-95.plesk.page\/home\/"},"modified":"2025-04-03T15:11:20","modified_gmt":"2025-04-03T14:11:20","slug":"home","status":"publish","type":"page","link":"https:\/\/www.aspire-ftd.com\/it\/","title":{"rendered":"Pagina iniziale"},"content":{"rendered":"

[et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.22.1″ _module_preset=”default” background_enable_color=”off” use_background_color_gradient=”on” background_color_gradient_direction=”90deg” background_color_gradient_stops=”rgba(10,0,1,0.45) 0%|rgba(0,0,0,0) 100%” background_color_gradient_overlays_image=”on” background_color_gradient_start=”rgba(67,67,79,0.6)” background_color_gradient_end=”rgba(0,0,0,0)” background_image=”https:\/\/www.aspire-ftd.com\/wp-content\/uploads\/2023\/08\/AviadoBio-Web-clinicaltrial-Banner.jpg” min_height=”500px” min_height_tablet=”400px” min_height_phone=”400px” min_height_last_edited=”on|phone” height_tablet=”” height_phone=”” height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”||||false|false” custom_margin_phone=”||||false|false” custom_margin_last_edited=”off|desktop” custom_padding=”20vh||40vh||false|false” custom_padding_tablet=”||40vh||false|false” custom_padding_phone=”30vh||50vh||false|false” bottom_divider_style=”ramp” bottom_divider_color=”#ffffff” bottom_divider_flip=”vertical” background_last_edited=”on|tablet” use_background_color_gradient_tablet=”on” background_color_gradient_stops_tablet=”rgba(10,0,1,0.45) 56%|rgba(0,0,0,0) 100%” global_colors_info=”{}”][et_pb_row column_structure=”3_4,1_4″ _builder_version=”4.24.2″ _module_preset=”default” positioning=”absolute” position_origin_a=”center_center” position_origin_f=”center_center” custom_margin=”0px||||false|false” custom_padding=”20px||||false|false” custom_css_main_element=”margin:auto !important” global_colors_info=”{}”][et_pb_column type=”3_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.aspire-ftd.com\/wp-content\/uploads\/2023\/11\/AspireFTD-Logo-White.png” title_text=”AspireFTD-Logo-White” _builder_version=”4.22.1″ _module_preset=”default” max_width=”350px” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.22.1″ _module_preset=”default” header_font=”||||||||” header_text_color=”#ffffff” header_font_size=”40px” header_line_height=”1.4em” header_2_font=”SweetSans Light||||||||” header_2_text_color=”#ffffff” header_2_font_size=”55px” max_width=”900px” custom_margin=”||0px||false|false” custom_padding=”||||false|false” animation_style=”fade” header_font_size_tablet=”” header_font_size_phone=”24px” header_font_size_last_edited=”on|phone” global_colors_info=”{}” header_font_size__hover_enabled=”off|desktop”]<\/p>\n

Sperimentazione clinica per la demenza frontotemporale con mutazioni di GRN<\/h1>\n

[\/et_pb_text][et_pb_text _builder_version=”4.22.1″ _module_preset=”default” text_font=”SweetSans Light||||||||” text_text_color=”#ffffff” text_font_size=”24px” text_line_height=”1.3em” header_2_text_color=”#43464F” header_2_font_size=”34px” header_2_letter_spacing=”2px” header_2_line_height=”1.4em” max_width=”700px” custom_margin=”0px||0px||false|false” custom_padding=”||||false|false” text_font_size_tablet=”” text_font_size_phone=”21px” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]Informazioni per i\/le pazienti affetti\/e da FTD e per i loro accompagnatori familiari o professionali
\n[\/et_pb_text][et_pb_divider show_divider=”off” disabled_on=”off|on|on” _builder_version=”4.22.1″ _module_preset=”default” height=”40px” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.22.1″ _module_preset=”default” background_image=”https:\/\/www.aspire-ftd.com\/wp-content\/uploads\/2023\/11\/Aspire-ftd-AviadoBio-Logo-Element-v1.png” background_size=”custom” background_image_height=”100%” background_position=”center_right” custom_margin=”0px||||false|false” custom_padding=”10vh||0px||false|false” custom_padding_tablet=”5vh||0px||false|false” custom_padding_phone=”” background_last_edited=”on|tablet” background_enable_image_tablet=”off” global_colors_info=”{}”][et_pb_row column_structure=”2_3,1_3″ make_equal=”on” custom_padding_last_edited=”on|phone” _builder_version=”4.24.2″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” width_tablet=”80%” width_last_edited=”off|desktop” module_alignment=”center” custom_margin=”||||false|false” custom_padding=”0px||0px||false|false” custom_padding_tablet=”” custom_padding_phone=”” module_alignment_tablet=”center” module_alignment_phone=”center” module_alignment_last_edited=”off|desktop” global_colors_info=”{}”][et_pb_column type=”2_3″ _builder_version=”4.16″ _module_preset=”default” custom_css_main_element=”margin:auto;” global_colors_info=”{}”][et_pb_text _builder_version=”4.24.2″ _module_preset=”default” header_font=”|||on|||||” header_2_font=”|||on|||||” header_2_text_color=”#43464F” header_2_letter_spacing=”2px” header_2_line_height=”1.4em” module_alignment=”left” custom_margin=”0px||0px||false|false” custom_padding=”0px||5vh||false|false” header_2_font_size_tablet=”” header_2_font_size_phone=”24px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n

AVIADOBIO: CHASING CURES. DELIVERING HOPE.\u2122<\/h2>\n

In AviadoBio siamo alla continua ricerca di cure, traducendo la scienza innovativa e la somministrazione di precisione in farmaci potenzialmente in grado di cambiare la vita delle persone affette da malattie neurologiche, a partire dalla demenza frontotemporale (FTD) e dalla sclerosi laterale amiotrofica (SLA).<\/p>\n

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ASPIRE-FTD \u00e8 uno studio in aperto multicentrico di fase 1\/2 progettato per valutare la sicurezza e l\u2019efficacia preliminare di AVB-101 in pazienti con FTD-GRN.<\/p>\n

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AVB-101 viene somministrato utilizzando una procedura neurochirurgica direttamente al talamo presso centri neurochirurgici specializzati in tutta Europa e negli Stati Uniti.<\/p>\n

 <\/p>\n

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AVB-101 \u00e8 una terapia sperimentale una tantum progettata per fornire una copia funzionale del gene progranulina (GRN) direttamente al cervello, ripristinando potenzialmente i livelli di progranulina e interrompendo la progressione della malattia nei\/lle pazienti con FTD-GRN.<\/p>\n

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I\/Le partecipanti idonei\/e devono avere un\u2019et\u00e0 compresa tra 30 e 75 anni, con diagnosi di FTD-GRN (confermata con un test genetico) e avere un accompagnatore familiare o professionale in grado di supportarli (incluse le visite dello studio) per tutta la durata dello studio (5 anni e 3 mesi).<\/p>\n

Esistono altri criteri che determinano l\u2019idoneit\u00e0, che possono essere discussi con un operatore sanitario.<\/p>\n

[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|tablet” _builder_version=”4.22.1″ _module_preset=”default” background_color=”#ffffff” custom_margin=”||||false|false” custom_padding=”0px||20vh||false|false” custom_padding_tablet=”” custom_padding_phone=”0px||20vh||false|false” bottom_divider_style=”ramp” bottom_divider_color=”#43464F” bottom_divider_flip=”vertical|horizontal” global_colors_info=”{}”][et_pb_row column_structure=”3_4,1_4″ use_custom_gutter=”on” gutter_width=”1″ _builder_version=”4.24.2″ _module_preset=”default” background_color=”#26B2B6″ custom_margin=”0px||||false|false” custom_padding=”30px|30px|30px|30px|true|true” global_colors_info=”{}”][et_pb_column type=”3_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.22.1″ _module_preset=”default” header_2_text_align=”left” header_2_text_color=”#ffffff” header_2_font_size=”24px” header_2_line_height=”1.4em” custom_margin=”0px||0px||false|false” custom_margin_tablet=”||3vh||false|false” custom_margin_phone=”” custom_margin_last_edited=”on|tablet” custom_padding=”10px||0px||false|false” header_2_text_align_tablet=”center” header_2_text_align_phone=”center” header_2_text_align_last_edited=”on|tablet” header_2_font_size_tablet=”24px” header_2_font_size_phone=”22px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n

La Policy di AviadoBio sull\u2019accesso allargato alle terapie sperimentali<\/h2>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjM0MzgifX0=@” button_text=”Visualizza la Policy” button_alignment=”right” button_alignment_tablet=”center” button_alignment_phone=”” button_alignment_last_edited=”on|tablet” _builder_version=”4.22.1″ _dynamic_attributes=”button_url” _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#ffffff” button_bg_color=”#43464F” button_border_width=”0px” button_border_color=”#26B2B6″ button_border_radius=”0px” button_letter_spacing=”3px” button_font=”SweetSans Medium|||on|||||” button_use_icon=”off” background_layout=”dark” custom_margin=”2px|0px|0px||false|false” custom_padding=”10px|40px|10px|40px|true|true” global_colors_info=”{}” button_bg_color__hover_enabled=”on|hover” button_bg_color__hover=”#ffffff” button_bg_enable_color__hover=”on” button_border_color__hover_enabled=”on|hover” button_border_color__hover=”#9F1D20″ button_text_color__hover_enabled=”on|hover” button_text_color__hover=”#43464F”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Sperimentazione clinica per la demenza frontotemporale con mutazioni di GRNInformazioni per i\/le pazienti affetti\/e da FTD e per i loro accompagnatori familiari o professionali AVIADOBIO: CHASING CURES. DELIVERING HOPE.\u2122 In AviadoBio siamo alla continua ricerca di cure, traducendo la scienza innovativa e la somministrazione di precisione in farmaci potenzialmente in grado di cambiare la vita […]<\/p>\n","protected":false},"author":1,"featured_media":5970,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"yoast_head":"\nASPIRE-FTD<\/title>\n<meta name=\"description\" content=\"Aspire-FTD - Sperimentazione clinica per la demenza frontotemporale con mutazioni di GRN - Informazioni per i\/le pazienti affetti\/e da FTD e per i loro accompagnatori familiari o professionali\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.aspire-ftd.com\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ASPIRE-FTD\" \/>\n<meta property=\"og:description\" content=\"Aspire-FTD - 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